Milos D Ikonomovic Selected Research

flutemetamol

6/2023	The flutemetamol analogue cyano-flutemetamol detects myocardial AL and ATTR amyloid deposits: a post-mortem histofluorescence analysis.
1/2021	Visual assessment of [18F]flutemetamol PET images can detect early amyloid pathology and grade its extent.
10/2020	Post-mortem analyses of PiB and flutemetamol in diffuse and cored amyloid-β plaques in Alzheimer's disease.
1/2018	Infrequent false positive [18F]flutemetamol PET signal is resolved by combined histological assessment of neuritic and diffuse plaques.
1/2017	Performance of [18F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA-AA recommendations for the neuropathologic diagnosis of Alzheimer's disease.
12/2016	Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection.
3/2015	Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Milos D Ikonomovic Research Topics

Disease

66	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 02/2002
17	Dementia (Dementias) 01/2024 - 02/2002
16	Cognitive Dysfunction 11/2023 - 02/2002
14	Amyloid Plaque 06/2023 - 03/2003
11	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022 - 12/2002
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 05/2009
5	Amyloidosis 06/2023 - 10/2018
5	Brain Injuries (Brain Injury) 06/2013 - 05/2004
4	Down Syndrome (Down's Syndrome) 01/2021 - 01/2016
4	Chronic Traumatic Encephalopathy 01/2020 - 09/2014
4	Tauopathies 01/2017 - 09/2014
3	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2021 - 11/2015
3	Atrophy 01/2018 - 12/2016
3	Death (Near-Death Experience) 01/2017 - 03/2015
2	Inflammation (Inflammations) 01/2020 - 01/2019
2	Psychotic Disorders (Schizoaffective Disorder) 10/2018 - 12/2012
2	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 02/2016 - 11/2015
2	Disease Progression 05/2009 - 12/2007
1	Clinical Deterioration 01/2023
1	Gliosis 10/2022
1	Infections 01/2021
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021
1	Coma (Comas) 11/2020
1	Brain Ischemia (Cerebral Ischemia) 01/2019
1	Prodromal Symptoms 01/2019
1	Parkinsonian Disorders (Parkinsonism) 01/2019
1	Schizophrenia (Dementia Praecox) 01/2017
1	Neurobehavioral Manifestations 01/2017
1	Intellectual Disability (Idiocy) 01/2016
1	Brain Concussion (Cerebral Concussion) 01/2016
1	Trisomy (Trisomies) 01/2016
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 11/2015
1	Multiple System Atrophy 11/2015
1	Corticobasal Degeneration 11/2015
1	Hyperemia 06/2013

Drug/Important Bio-Agent (IBA)

37	Amyloid (Amyloid Fibrils)IBA 01/2024 - 12/2002
15	Amyloid beta-PeptidesIBA 01/2021 - 12/2002
14	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2002
12	Peptides (Polypeptides)IBA 01/2021 - 12/2002
11	Biomarkers (Surrogate Marker)IBA 01/2023 - 04/2013
10	Cholinergic Agents (Cholinergics)IBA 01/2016 - 02/2002
8	EnzymesIBA 04/2016 - 02/2003
7	flutemetamolIBA 06/2023 - 03/2015
7	Nerve Growth Factor (NGF)IBA 01/2019 - 08/2003
6	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 04/2015 - 02/2002
4	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2022 - 11/2005
3	LigandsIBA 01/2017 - 09/2014
3	AntibodiesIBA 04/2016 - 12/2008
2	neurabinIBA 01/2023 - 01/2017
2	Pyrrolidonecarboxylic Acid (Pyroglutamic Acid)IBA 01/2021 - 01/2015
2	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 01/2020 - 01/2017
2	Protein AggregatesIBA 01/2020 - 01/2006
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2019 - 02/2004
2	tau Proteins (tau Protein)IBA 01/2019 - 01/2017
2	SynucleinsIBA 01/2019 - 11/2015
2	Glutamic Acid (Glutamate)FDA Link 01/2016 - 10/2003
2	Apolipoproteins E (ApoE)IBA 01/2016 - 04/2007
2	Simvastatin (Zocor)FDA LinkGeneric 06/2013 - 09/2009
2	Neurotransmitter Agents (Neurotransmitter)IBA 10/2011 - 05/2005
2	ImmunosorbentsIBA 05/2009 - 08/2003
2	hnRNP A2IBA 09/2005 - 12/2004
2	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 09/2005 - 12/2004
2	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2004 - 05/2004
2	AntioxidantsIBA 08/2004 - 05/2004
1	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 06/2023
1	Prealbumin (Transthyretin)IBA 06/2023
1	formic acid (formate)IBA 06/2023
1	Glial Fibrillary Acidic ProteinIBA 01/2023
1	Vesicular Glutamate Transport ProteinsIBA 01/2023
1	Monoamine Oxidase (MAO)IBA 10/2022
1	salicylhydroxamic acid (SHAM)IBA 01/2022
1	Coloring Agents (Dyes)IBA 01/2021
1	thioflavin TIBA 01/2021
1	RadiopharmaceuticalsIBA 01/2021
1	Blood Proteins (Serum Proteins)IBA 01/2020
1	Memantine (Namenda)FDA Link 01/2019
1	Nerve Growth Factors (Neurotrophins)IBA 01/2019
1	Becaplermin (PDGF-BB)FDA Link 01/2019
1	Retinaldehyde (Retinal)IBA 01/2019
1	CytokinesIBA 01/2019
1	ProteomeIBA 10/2018
1	GuanineIBA 01/2017
1	ButyrylcholinesteraseIBA 04/2016
1	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2016
1	AcetylcholinesteraseIBA 04/2016
1	NeurocalcinIBA 02/2016
1	CalciumIBA 02/2016
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2016
1	Choline (Choline Chloride)IBA 01/2016
1	Glycoproteins (Glycoprotein)IBA 01/2016
1	TenascinIBA 01/2016
1	Apolipoprotein E4IBA 01/2016
1	EmulsionsIBA 11/2015
1	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2015
1	FluorineIBA 03/2015
1	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2014
1	UbiquitinIBA 02/2014

Therapy/Procedure

7	Therapeutics 11/2020 - 02/2002
1	Immunotherapy 01/2021
1	Drug Therapy (Chemotherapy) 10/2018